European medical studies suggest that the answer is yes, bio-identical hormones are safer than synthetic versions. This makes perfect sense. But we must be cautious here, because the FDA labels all types of hormone replacements with the same warnings until when and if further evidence is presented. Everything in medicine is determined by risk, benefit, and informed consent. The more educated and informed patients are the better it is. We work together with our patients to optimize their health using the appropriate hormones properly when indicated.